More than 20 million people in the United States are estimated to have some form of Peripheral Neuropathy (PN). PN occurs when nerves are damaged or destroyed by disease or injury. The injured nerves either no longer communicate impulses like a broken wire, or they signal inappropriately like static on a phone line. Other times, signals may be distorted like a wavy television picture.

Neuropathy can also impair the function of the microvasculature (tiny blood vessels) in the extremities, and often the furthest nerve endings in the feet are affected first, or are the most seriously affected.

Symptoms can be brought on by diseases like diabetes, or as a result of viral infection or chemotherapy and include tingling, numbness, and shooting pains in the feet and legs, which can be worse at night.

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